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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q08170
USC-OGP 2-DE database
:
Q08170
Q08170
General information about the entry
View entry in simple text format
Entry name
SRSF4_HUMAN
Primary accession number
Q08170
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Serine/arginine-rich splicing factor 4; AltName: Full=Pre-mRNA-splicing factor SRP75; AltName: Full=SRP001LB; AltName: Full=Splicing factor, arginine/serine-rich 4;.
Gene name
Name=SRSF4
Synonyms=SFRS4, SRP75
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1095
:
pI=5.32; Mw=148989
Cross-references
UniProtKB/Swiss-Prot
Q08170; SRSF4_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
SRSF4_HUMAN
Primary accession number
Q08170
Secondary accession number(s)
Q5VXP1 Q9BUA4 Q9UEB5
Sequence was last modified on
May 15, 2002 (version 2)
Annotations were last modified on
March 15, 2017 (version 169)
Name and origin of the protein
Description
RecName: Full=Serine/arginine-rich splicing factor 4; AltName: Full=Pre-mRNA-splicing factor SRP75; AltName: Full=SRP001LB; AltName: Full=Splicing factor, arginine/serine-rich 4;
Gene name
Name=SRSF4
Synonyms=SFRS4, SRP75
Encoded on
Name=SRSF4; Synonyms=SFRS4, SRP75
Keywords
Complete proteome
;
Direct protein sequencing
;
mRNA processing
;
mRNA splicing
;
Nucleus
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Repeat
;
Repressor
;
RNA-binding
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
L14076; AAA36649.1
; -; mRNA
EMBL
BT007415; AAP36083.1
; -; mRNA
EMBL
AL590729; CAI14326.1
; -; Genomic_DNA
EMBL
AL357500; CAI14326.1
; JOINED; Genomic_DNA
EMBL
AL357500; CAH71635.1
; -; Genomic_DNA
EMBL
AL590729; CAH71635.1
; JOINED; Genomic_DNA
EMBL
BC002781; AAH02781.1
; -; mRNA
EMBL
AC004236; AAC04476.1
; -; Genomic_DNA
CCDS
CCDS333.1; -
; .
PIR
A48133; A48133
; .
RefSeq
NP_005617.2; NM_005626.4
; .
UniGene
Hs.469970; -
; .
ProteinModelPortal
Q08170; -
; .
SMR
Q08170; -
; .
BioGrid
112327; 42
; .
IntAct
Q08170; 28
; .
MINT
MINT-1410521; -
; .
STRING
9606.ENSP00000362900; -
; .
iPTMnet
Q08170; -
; .
PhosphoSitePlus
Q08170; -
; .
SwissPalm
Q08170; -
; .
BioMuta
SRSF4; -
; .
DMDM
20981726; -
; .
EPD
Q08170; -
; .
MaxQB
Q08170; -
; .
PaxDb
Q08170; -
; .
PeptideAtlas
Q08170; -
; .
PRIDE
Q08170; -
; .
DNASU
6429; -
; .
Ensembl
ENST00000373795; ENSP00000362900
; ENSG00000116350; .
GeneID
6429; -
; .
KEGG
hsa:6429; -
; .
UCSC
uc001bro.4; human
; .
CTD
6429; -
; .
DisGeNET
6429; -
; .
GeneCards
SRSF4; -
; .
H-InvDB
HIX0160019; -
; .
HGNC
HGNC:10786; SRSF4
; .
HPA
HPA050975; -
; .
MIM
601940; gene
; .
neXtProt
NX_Q08170; -
; .
OpenTargets
ENSG00000116350; -
; .
PharmGKB
PA35702; -
; .
eggNOG
KOG0106; Eukaryota
; .
eggNOG
COG0724; LUCA
; .
GeneTree
ENSGT00700000104103; -
; .
HOVERGEN
HBG002295; -
; .
InParanoid
Q08170; -
; .
KO
K12893; -
; .
OMA
KSKDHAE; -
; .
OrthoDB
EOG091G0R9W; -
; .
PhylomeDB
Q08170; -
; .
TreeFam
TF351335; -
; .
Reactome
R-HSA-109688; Cleavage of Growing Transcript in the Termination Region
; .
Reactome
R-HSA-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript
; .
Reactome
R-HSA-72163; mRNA Splicing - Major Pathway
; .
Reactome
R-HSA-72187; mRNA 3'-end processing
; .
ChiTaRS
SRSF4; human
; .
GeneWiki
SFRS4; -
; .
GenomeRNAi
6429; -
; .
PRO
PR:Q08170; -
; .
Proteomes
UP000005640; Chromosome 1
; .
Bgee
ENSG00000116350; -
; .
CleanEx
HS_SFRS4; -
; .
ExpressionAtlas
Q08170; baseline and differential
; .
Genevisible
Q08170; HS
; .
GO
GO:0016607; C:nuclear speck
; IDA:HPA; .
GO
GO:0005654; C:nucleoplasm
; TAS:Reactome; .
GO
GO:0005634; C:nucleus
; TAS:ProtInc; .
GO
GO:0000166; F:nucleotide binding
; IEA:InterPro; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:1990825; F:sequence-specific mRNA binding
; IEA:Ensembl; .
GO
GO:0031124; P:mRNA 3'-end processing
; TAS:Reactome; .
GO
GO:0006406; P:mRNA export from nucleus
; TAS:Reactome; .
GO
GO:0006397; P:mRNA processing
; TAS:ProtInc; .
GO
GO:0000398; P:mRNA splicing
; via spliceosome; TAS:Reactome
GO
GO:0048025; P:negative regulation of mRNA splicing
; via spliceosome; IDA:UniProtKB
GO
GO:0032868; P:response to insulin
; IEA:Ensembl; .
GO
GO:0006405; P:RNA export from nucleus
; TAS:Reactome; .
GO
GO:0008380; P:RNA splicing
; TAS:ProtInc; .
GO
GO:0000375; P:RNA splicing
; via transesterification reactions; TAS:ProtInc
GO
GO:0006369; P:termination of RNA polymerase II transcription
; TAS:Reactome; .
Gene3D
3.30.70.330; -
; 2; .
InterPro
IPR012677; Nucleotide-bd_a/b_plait
; .
InterPro
IPR000504; RRM_dom
; .
Pfam
PF00076; RRM_1
; 2; .
SMART
SM00360; RRM
; 2; .
SUPFAM
SSF54928; SSF54928
; 1; .
PROSITE
PS50102; RRM
; 2; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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